Scope of the Symposium

The aim of the joint Swiss-Czech and BioTech2005 symposium is to generate discussion on the further potential of the industrial exploitation of yeasts such as Pichia, Saccharomyces, Hansenula and the like. Although commercially relevant products such as therapeutic proteins and enzymes can be expressed in yeast, at present there is only limited use of yeast in their industrial production. However, a number of noteworthy developments have recently stimulated the renaissance of yeast biotechnology, e.g. yeast’s potential for humanized glycosylation as well as its ability to secrete large amounts of proteins. Furthermore, as a fast-growing organism, yeast can be easily cultivated to high cell densities in non-expensive mineral media, and is therefore free from retroviral contaminations as well as being easy to handle at large scale.
In order to assess the further potential and limitations of industrial production using yeast expression systems, the following topical issues will be addressed during the symposium:

•  yeast genetics and posttranslational modifications,
•  yeast physiology and metabolism,
•  potential application of yeast and yeast products,
•  challenges in industrial production with yeasts,

academic and industrial networking and opportunities for international co-operation.

In order to assess the extent to which innovation in yeast biology and process technology might contribute to the competitiveness of yeasts, the expression systems of industrially interesting species will be compared with respect to their physiological and metabolic characteristics. In addition, an overview of existing products will be made and possible future products identified. Through taking part in the symposium, participants will gain a comprehensive survey of potential new applications of yeasts in biotechnology as well as innovative ideas from academia and industry.

biotech 2005

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